VA Product

Vocabulary_ID=28

The following describes the procedure to update the VA Product vocabulary (concepts, synonyms, relationships, ancestry) with the latest release of the source.

The load process is a complete refresh of data. All new vocabulary entieties will be added. All vocabulary entities that do not exist in the latest files set will be marked as deprecated.

1.1 Scripts Transfer

All scripts and files listed at the bottom of this page should be transferred to specially created directory (eg /data/VAPROD).

Script Name	Description
28_create_schema.sql	Create prestage-stage schema with tables and indexes
28_load_to_prestage.sh	Load RxNorm row-data
28_transform_row_concepts.sql	Convert and store in stage table concept_stage
28_load_concepts.sql	Load only new concepts into concept table, add invalid code information
28_transform_row_relations.sql	Convert and store in stage table concept_relationship_stage
28_load_relations.sql	Load only new relationships into relationship table, add invalid code information.
28_transform_row_maps.sql	Convert and store in stage table SOURCE_TO_CONCEPT_MAP_STAGE
28_load_maps.sql	Load only new maps into SOURCE_TO_CONCEPT_MAP table, add invalid code information

1.2 Download data from source

The most current international release is located at the following URL: http://www.nlm.nih.gov/research/umls/rxnorm/docs/rxnormfiles.html

Historical archives located at: http://www.nlm.nih.gov/research/umls/rxnorm/docs/rxnormarchive.html

Note: Make sure you perform updates in chronological order. So, if you want to process a January and April release, execute the below steps for January, and after successful completion, for April.

Download the latest release file (e.g. RxNorm_full_08062012.zip)
Transfer downloaded zip file to /data/VAPROD directory.

Zip file suffix contains release date (e.g. 08062012=06-Aug-2012)
Latest production zip file is ~131MB in size

Note: For the rest of the document we will be referring to current schema as VAPROD_20120806 you would have to adjust this entry to correspond to current release date file

1.3 Build Database Schema

All tables will be located in the schema SNOMED_<DateOfSourceFile> as following: VAPROD_20120131
The following steps will create a schema and will grant to a schema owner appropriate permissions.

In addition to the schema, it will create tables to load raw data: RXNATOMARCHIVE,RXNCONSO,RXNCUI,RXNCUICHANGES,RXNDOC,RXNREL,RXNSAB,RXNSAT and RXNSTY as well as staging tables:

CONCEPT_STAGE,

CONCEPT_ANCESTOR_STAGE,

CONCEPT_RELATIONSHIP_STAGE,
SOURCE_TO_CONCEPT_MAP_STAGE

$ sqlplus System/<SystemPass>@DEV_VOCAB @28_create_schema.sql <VAPROD_Schema> <Pass_VAPROD_Schema>

Format of VAPROD_Schema should be VAPROD_YYYYMMDD (e.g. VAPROD_20120806)

Staging tables match Vocabulary schema version 4.0 with slight modification. Modifications made to the tables are:

CONCEPT_STAGE.CONCEPT_ID is nullable

CONCEPT_RELATIONSHIP_STAGE

.REL_ID is nullable

1.4 Raw data load into Oracle tables

1.4.1 Extract files from the zip archive into the current directory

$ unzip -u RxNorm_full_08062012.zip -d rxnorm_20120806

1.4.2 Verify that the following 2 files have been created:

RXNCONSO.RRF (Latest file size ~96MB)

RXNATOMARCHIVE.RRF (Latest file size ~42MB)

RXNCUI.RRF (Latest file size ~1MB)

RXNCUICHANGES.RRF (Latest file size ~1MB)

RXNDOC.RRF (Latest file size ~1MB)

RXNREL.RRF (Latest file size ~230MB)

RXNSAB.RRF (Latest file size ~8KB)

RXNSAT.RRF (Latest file size ~385MB)

RXNSTY.RRF (Latest file size ~15MB)

1.4.4. Load raw data into Oracle.

      This sqlldr process will run for about 2min.
       $ ./28_load_to_prestage.sh /data/VAPROD/rxnorm_20120806 <VAPROD_Schema>/<Pass_VAPROD_Schema>
1.4.4.1 Verify that files with extension .bad are empty, no records have been rejected.

1.4.4.2 Copy data and intermediate files to backup area. In this step, downloaded files will be archived to preserve source of the data. Discuss a location of backup area with your system administrator.

       $ cp -Ru /data/VAPROD/*.zip /data/backup_area ; cp -Ru /data/VAPROD/*.log /data/backup_area
1.4.4.3 Verify that number of records loaded is equivalent to prior production load

$ sqlplus VAPROD_20120806/myPass@DEV_VOCAB

Execute the following SQL commands:

SELECT count(*) FROM RXNCONSO;

Current production row count is: 979,203 Rows

SELECT count(*) FROM RXNREL;

Current production row count is: 3,485,382 Rows

1.5 Loading Staging Tables from raw

1.5.1 Convert and store in staging table concepts

Loaded from raw staged data RXNCONSO into the staged data CONCEPT_STAGE
In this step we will perform substitute GUID identifiers into numerical format.

$ sqlplus VAPROD_20120806/myPass@DEV_VOCAB @28_transform_row_concepts.sql

1.5.2 Verify that number of records loaded is equivalent to prior production load
In this step we will verify that number of active records in staging tables is valid prior to transfer data to historical DEV schema.

a. Number of Records in stage table

b. Number of records in DEV schema not deleted (active, prior load production)

c. How many records would be added to DEV schema table

d. How many active DEV records will be marked for deletion

In most cases number of records in stage (a) should be greater than number of active records in production (b)
In rare occasion that might not be the case. It is responsibility of the developer running the scripts to verify that that is the the valid.

$ sqlplus VAPROD_20120806/myPass@DEV_VOCAB

Execute the following SQL commands:

SELECT '- Num Rec in stage' AS scr, COUNT (8) cnt
FROM CONCEPT_STAGE c
WHERE C.VOCABULARY_ID = 28
UNION ALL
SELECT '- Num Rec in DEV not deleted' AS scr, COUNT (8) cnt
FROM DEV.CONCEPT d
WHERE d.VOCABULARY_ID = 28 AND NVL (d.INVALID_REASON, 'X') <> 'D'
UNION ALL
SELECT '- How many records would be new in DEV added' AS scr, COUNT (8) cnt
FROM CONCEPT_STAGE c
WHERE C.VOCABULARY_ID = 28
       AND NOT EXISTS
              (SELECT 1
                 FROM DEV.CONCEPT d
                WHERE d.VOCABULARY_ID = 28 AND c.CONCEPT_CODE = D.CONCEPT_CODE)
UNION ALL
SELECT '- How many DEV active will be marked for deletion' AS scr,
       COUNT (8) cnt
FROM DEV.CONCEPT d
WHERE     d.VOCABULARY_ID = 28
       AND NVL (d.INVALID_REASON, 'X') <> 'D'
       AND NOT EXISTS
              (SELECT 1
                 FROM CONCEPT_STAGE c
                WHERE c.VOCABULARY_ID = 28 AND c.CONCEPT_CODE = D.CONCEPT_CODE);

Current Result:
- Num Rec in stage          16344
- Num Rec in DEV not deleted           16195
- How many records would be new in DEV added        149
- How many DEV active will be marked for deletion       0

1.5.3   Load new concepts into DEV schema concept table,mark deprecated concepts as deleted. Valid start date, valid end date and invalid reason are left empty for now.
       Transfer records from CONCEPT_STAGE to DEV.CONCEPT table

   $  sqlplus  VAPROD_20120806/myPass@DEV_VOCAB @28_load_concepts.sql

1.5.4    Load new concept relationships stage, identify invalid codes  information
Loaded from the raw staged data RXNREL into the staged data CONCEPT_RELATIONSHIP_STAGE, identify invalid code information

$  sqlplus  VAPROD_20120806/myPass@DEV_VOCAB @28_transform_row_relations.sql

1.5.5 Verify that number of records loaded is equivalent to prior production load

SELECT '- Num Rec in stage' AS scr, COUNT (8) cnt
FROM CONCEPT_RELATIONSHIP_STAGE d
WHERE     EXISTS
              (SELECT 1
                 FROM DEV.CONCEPT c
                WHERE c.VOCABULARY_ID IN ( 28) AND c.CONCEPT_ID = CONCEPT_ID_1)
UNION ALL
SELECT '- Num Rec in DEV not deleted' AS scr, COUNT (8) cnt
FROM DEV.CONCEPT_RELATIONSHIP d
WHERE     EXISTS
              (SELECT 1
                 FROM DEV.CONCEPT c
                WHERE c.VOCABULARY_ID IN ( 28) AND c.CONCEPT_ID = CONCEPT_ID_1)
AND NVL(d.INVALID_REASON, 'X') <> 'D'
UNION ALL
SELECT '- How many records would be new in DEV added' AS scr, COUNT (8) cnt
FROM CONCEPT_RELATIONSHIP_STAGE c
WHERE NOT EXISTS
              (SELECT 1
                 FROM DEV.CONCEPT_RELATIONSHIP d
                WHERE     c.CONCEPT_ID_1 = d.CONCEPT_ID_1
                      AND c.CONCEPT_ID_2 = d.CONCEPT_ID_2
                      AND c.RELATIONSHIP_ID = d.RELATIONSHIP_ID)
AND EXISTS
              (SELECT 1
                 FROM DEV.CONCEPT c
                WHERE c.VOCABULARY_ID IN ( 28) AND c.CONCEPT_ID = CONCEPT_ID_1)
UNION ALL
SELECT '- How many DEV active will be marked for deletion' AS scr,
       COUNT (8) cnt
FROM DEV.CONCEPT_RELATIONSHIP d
WHERE     EXISTS
              (SELECT 1
                 FROM DEV.CONCEPT c
                WHERE c.VOCABULARY_ID IN ( 28) AND c.CONCEPT_ID = CONCEPT_ID_1)
       AND NVL(d.INVALID_REASON, 'X') <> 'D'
       AND NOT EXISTS
                  (SELECT 1
                     FROM CONCEPT_RELATIONSHIP_STAGE c
                    WHERE     c.CONCEPT_ID_1 = d.CONCEPT_ID_1
                          AND c.CONCEPT_ID_2 = d.CONCEPT_ID_2
                          AND c.RELATIONSHIP_ID = d.RELATIONSHIP_ID);
Current Result:
- Num Rec in stage    149867
- Num Rec in DEV not deleted                 147175
- How many records would be new in DEV added              1357
- How many DEV active will be marked for deletion           100

1.5.6    Load new concept relationships into DEV schema,mark deprecated concept relatuionships as deleted
Transfer records from CONCEPT_RELATIONSHIP_STAGE to DEV.CONCEPT_RELATIONSHIP table

     $  sqlplus   VAPROD_20120806/myPass@DEV_VOCAB @28_load_relations.sql

1.5.7 Convert and store in staging table maps

Loaded from raw staged data RXNCONSO into the staged data SOURCE_TO_CONCEPT_MAP_STAGE

           $  sqlplus  VAPROD_20120806/myPass@DEV_VOCAB @28_transform_row_maps.sql

1.5.8 Verify that number of records loaded is equivalent to prior production load
In this step we will verify that number of active records in staging tables is valid prior to transfer data to historical DEV schema.
   a. Number of Records in stage table
   b. Number of records in DEV schema not deleted (active, prior load production)
   c. How many records would be added to DEV schema table
             d. How many active DEV records will be marked for deletion

   In most cases number of records in stage (a) should be greater than number of active records in production (b)
In rare occasion that might not be the case. It is responsibility of the developer running the scripts to verify that that is the the valid.

    $ sqlplus  VAPROD_20120806/myPass@DEV_VOCAB

  Execute the following SQL commands:
SELECT '- Num Rec in stage' AS scr, COUNT (8) cnt
FROM SOURCE_TO_CONCEPT_MAP_STAGE c
WHERE c.SOURCE_VOCABULARY_ID IN (28)
UNION ALL
SELECT '- Num Rec in DEV not deleted' AS scr, COUNT (8) cnt
FROM DEV.SOURCE_TO_CONCEPT_MAP d
WHERE     d.SOURCE_VOCABULARY_ID IN (28)
       AND D.TARGET_VOCABULARY_ID IN (08)
       AND NVL (d.INVALID_REASON, 'X') <> 'D'
UNION ALL
SELECT '- How many records would be new in DEV added' AS scr, COUNT (8) cnt
FROM SOURCE_TO_CONCEPT_MAP_STAGE c
WHERE c.SOURCE_VOCABULARY_ID IN (28) AND c.TARGET_VOCABULARY_ID IN (08)
       AND NOT EXISTS
                  (SELECT 1
                     FROM DEV.SOURCE_TO_CONCEPT_MAP d
                    WHERE     d.SOURCE_VOCABULARY_ID IN (28)
                          AND c.SOURCE_CODE = D.SOURCE_CODE
                          AND d.SOURCE_VOCABULARY_ID = c.SOURCE_VOCABULARY_ID
                          AND d.MAPPING_TYPE = c.MAPPING_TYPE
                          AND d.TARGET_CONCEPT_ID = c.TARGET_CONCEPT_ID
                          AND d.TARGET_VOCABULARY_ID = c.TARGET_VOCABULARY_ID)
UNION ALL
SELECT '- How many DEV active will be marked for deletion' AS scr,
       COUNT (8) cnt
FROM DEV.SOURCE_TO_CONCEPT_MAP d
WHERE     d.SOURCE_VOCABULARY_ID IN (28)
       AND D.TARGET_VOCABULARY_ID IN (08)
       AND NVL (d.INVALID_REASON, 'X') <> 'D'
       AND d.VALID_START_DATE <
              TO_DATE (
                 SUBSTR (USER, REGEXP_INSTR (USER, '_[[:digit:]]') + 1, 256),
                 'YYYYMMDD')
       AND NOT EXISTS
                  (SELECT 1
                     FROM SOURCE_TO_CONCEPT_MAP_STAGE c
                    WHERE     c.SOURCE_VOCABULARY_ID IN (28)
                          AND c.SOURCE_CODE = D.SOURCE_CODE
                          AND d.SOURCE_VOCABULARY_ID = c.SOURCE_VOCABULARY_ID
                          AND d.MAPPING_TYPE = c.MAPPING_TYPE
                          AND d.TARGET_CONCEPT_ID = c.TARGET_CONCEPT_ID
                          AND d.TARGET_VOCABULARY_ID = c.TARGET_VOCABULARY_ID)
       AND EXISTS
              (SELECT 1
                 FROM SOURCE_TO_CONCEPT_MAP_STAGE c
                WHERE     d.SOURCE_CODE = c.SOURCE_CODE
                      AND d.SOURCE_VOCABULARY_ID = c.SOURCE_VOCABULARY_ID
                      AND d.MAPPING_TYPE = c.MAPPING_TYPE
                      AND d.TARGET_VOCABULARY_ID = c.TARGET_VOCABULARY_ID);

Current Result:
- Num Rec in stage           12814
- Num Rec in DEV not deleted          24994
- How many records would be new in DEV added     169
- How many DEV active will be marked for deletion 8

  1.5.9   Load new maps into DEV schema concept table,mark deprecated concepts as deleted.
           Valid start date, valid end date and invalid reason are left empty for now.
             Transfer records from SOURCE_TO_CONCEPT_MAP_STAGE to DEV.SOURCE_TO_CONCEPT_MAP table

$ sqlplus VAPROD_20120806/myPass@DEV_VOCAB @28_load_maps.sql